Images

Catherine Twomey, 2006. Photo Google scholar

http://dels-old.nas.edu/bls/stemcells/images/Embryonic-Download.JPG

 Summary:The image is plurpotent cells
Ascess:I will be useing this image.
Reflect:I will be using this image in my slideshow

 Paul J. Tesar, 2006. Photo Google scholar
http://en.wikipedia.org/wiki/File:Humanstemcell.JPG
Summary: The image is of a human stem cell
Assess: The source is useful to go with my content in my slideshow
Reflect: I will be using the image in my slide show

 Zoey Huang, 2012. Photo Google Scholar
http://newscenter.berkeley.edu/2012/06/06/stem-cells-vascular-disease/
Summary: The source is actual researchers in a topic that I will be using in my slideshow.
Assess: The source is useful in my research.
Reflect: I will be useing in my slideshow presentation.

 Cartoon about stem cell research and congress. 2011. Photo Google Scholar Images
http://www.thestemcellblog.com/wp-content/uploads/2011/01/stem_cells_cartoon.jpg
Summary: The image is a good reflection of my content.
Ascess: The source corisponds to my wrinings in my slideshow
Reflect: I will be useing in my slideshow

Sofia Ambrosia, 2011. Photo Google scholar
https://s3.amazonaws.com/healthtap-public/ht-staging/user_answer/reference_image/4275/large/Stem_Cells.jpeg?1349189886
Summary:The Image gives good visualation in regards to my content.
Ascess : The image gives my viewer a more relationship with my slideshow
Reflect: I will be useing this image in my slideshow

Slide show

Wednesday, October 31, 2012

slide show

My Idea for the slide show would be to first show some of the different stem cells and focus on the diseases. I would show the pictures of the diseases if at all possible and show some of the stages that occurr when there is no possible cure. I would also show the differnt surgerys performed when harvesting the different types of stem cells. I would try to  show pictures of reasearch projects that are currently going on to dipict the hours scientist put into the cure for each individual patient. I would also emphise how much of schooling each scientist has to go threw to get to be a reasearcher in a stem cell project. This would show that there is muck knowledge going into completeing the project themselves. I may even place some charts with stats showing the cures deaths and possible side effect deaths or worse out comes so that the patients can visually see both sides of the so called coin. I would also possibly show images of the scientist if I have or find. I would also maybe show at what stage would work best for the treatment to work opposed to being so far gone. Although some reasearchers need patients that are in different stages so that hopefilly they would be able to provide a cure for them then.







Posted by lisa f at 8:57 AM No comments:

interview

• What do I still need to know about my topic to successfully support my main idea? I need to gather more information so that I could take a new direction of thought. More toward the science aspect of stem cells.
• Who might be able to offer me that information in an interview? I believe either a hospital or a college who is currently in a reaseach project or clinical trial.
• Why would that person be considered an expert in the field? Dr lucy godley. because she is currenly running a clinical trial at the university of chicaho Medicine.
• What 3 questions can I ask this expert to  elicit the information I need to support my main idea in the webtext?What is your position and what is your day to day job? Is the same issue focused on each day? What is required from you as far as the scientific side? What is the difference in all of the types of stem cells you research by this I mean how you contain and keep them preserved for the scientific portion? Can a patient start noticing the effects of a successful stem cell Transplant right away or is there a length of time before you will know if it took?
• What is my next step to accomplish this field research? The next step would be to contact Lucy and see when would be a good time for her.

Interview protical

interview protical
Protocol



Stem cells and trials

1.     I will talk to someone who is a scientist who is working a clinical trial where stem cells are being studied.

2.     I will conduct this interview either via email or on the phone.

3.     My goal is to learn the effects on the stem cells themselves and what happens in the process of the trials on the scientific side.

4.     I will conduct this interview in formal and professional manner.

5.     I want to learn the effects on the study of the stem cells themselves and if all of the cells are used in the process and what happens in each step of the process.

6.     I want to learn from both a scientific and personal view on the stem cells studies exactly what ones are most productive in slowing or preventing which diseases.

7.     I want to know there stand on the issue as far as the laws and guide lines of clinical stem cells.



Contact information:

Dr. Lucy Godley

The University of Chicago Medicine
5841 S. Maryland Avenue
Chicago, IL 60637 | 773-702-1000



Questions:



What is your position and what is your day to day job? Is the same issue focused on each day? What is required from you as far as the scientific side?



What is the difference in all of the types of stem cells you research by this I mean how you contain and keep them preserved for the scientific portion?



Can a patient start noticing the effects of a successful stem cell Transplant right away or is there a length of time before you will know if it took?



In your opinion why is there so much controversy on embryonic and not so much on other types of stem cells when it comes to clinical trials?



Are there any cells that you notice right on harvesting or testing that you know will not work and how is it that you know this?



What happens in the trials with the funding when there aren’t enough patients for the trial?



Who makes for a healthy patient in harvesting the stem cells? Where do you most likely focus your retrieval from when cells are needed as far as family or random donors?



What does a dr or scientist go through when the transplants are not successful? Do you hold a meeting and try to find out where complications may have occurred or do you just chalk it up to the body just rejected it without further thought?

An Annotation and bibliographic entry

In the article it revels that they discovered that "embryonic stem cells express large proportions of their genome ( Hebrew University,2008)" by this they have discovered that tissues have specific genes. It is believed that because of this specific gene sequencing it unlocks their secrets to how they function and develop. But once this is gone the ability to understand goes with it. But at that point embryonic stells stand by attentively waiting to transform into what ever tissue the body calls on for it's need.


The Hebrew University of Jerusalem (2008, May 13). How Embryonic Stem Cells Develop Into Tissue-specific Cells Demonstrated. Retrieved from: http://www.sciencedaily.com/releases/2008/05/080512105729.htm



John B. Gurdon and Shinya Yamanaka have been recognised for discovering that embryonic stem cells can change into any tissue types in the human body and how they develop. Because of their studies they changed mature cells into reprogramming and becoming pluripotent stem cells. Because of these discoveries scientist changed there whole out look on disease study and new methods for diagnosing and developing cures medicine etc.



Nobel Foundation (2012, October 8). Nobel Prize in Physiology or Medicine 2012 awarded for discovery that mature cells can be. Retrieved from: http://www.sciencedaily.com/releases/2012/10/121008082955.htm

Midterm

Some of the issues I have related to my webtext is that although I do know a lot about computers I am not computer savy. I have had a few issues when it comes to researching some of my subject material in google scholars only because some of them want you to purchase the material prior to reading the whole piece. Another issue that I have encountered is the way to word specific issues without becoming too repetitive or boring to say the least. I find that some of my writing may be below that of scholorly at least this is my own personal opinion as far as how I would like the reader to understand and get the importance of my work. It has become hard to guide my threw the understanding of the fonts, them change and how to make the lay out how I would like it. I recently have seeked helped for this and have somewhat of a better understanding now. In my disscussion posts for this class they seem to be very helpful in relating to my webtext and be used as examples of work that needed to be placed the web text. I enjoy the writhing journals so far because it helps with gathering ideas on topics and different ideas. I am over coming these issues by going to the wring lab and emailing peers to proof read and rereading my material as often as possible.

pod

Stem cells have several different applications in basic research, drug discovery, and cell therapy. In basic research applications stem cells improve the ability to screen for side effects in many different drugs. Because of the use of stem cells at the beginning of the screenings of drugs there will be a lesser over head cost as well as the ability to scrap drugs that are extremely harmful or fatal. Because under current government standards animals are used to take the drugs and because of this the outcomes are different slightly because humans are made up of different cells and organelles the side effects on animals may not have none at all opposed to people. Because stem cells can regenerate and create new tissues the ability to create different organs to use to test on such as the heart or liver because of the harmful effects it had on individuals when they are administered powerful drugs. This would take medical science and drug researchers to a safer drug administered program for humans. This would mean that if the cells had high toxicity of drugs then they would not be available for clinical trials and the patients who are receiving them would go through fewer side effects. This would mean a cure possibly for tumors in embryonic stem cell research. Companies would be able to manufacture drugs that would be made for each independent trial instead of groups and finding out that fatal side effects occurred because of the risks to the patients.

Welcome

Welcome to my blog Eng 105. Lisa Filiczkowski.

annotated bib

International Society for stem cell research. (2010).Top ten things to know about stem cell research. International Society For Stem Cell Research. Retrieved from http://www.closerlookatstemcells.org/Top_10_Stem_Cell_Treatment_Facts.htm

Rister, Robert. (2011). Ten Things About Stem Cell Transplants Recipients Need To Know. Steady Health.com. Retrieved from 

http://www.steadyhealth.com/articles/Ten_Things_About_Stem_Cell_Transplants_Potential_Recipients_Need_To_Know_a1949.html

Image for stem cell

 Human Embryonic stem cell. (2004). All I know. Retrieved 9/17/2012 from 
http://www.google.com/imgres?hl=en&as_st=y&biw=1280&bih=880&tbs=sur:f&tbm=isch&tbnid=-yHlNXAobycAGM:&imgrefurl=http://rchrd.com/weblog/archives/archive_2004-m10.php&docid=7UTzbYaxacbwXM&imgurl=http://rchrd.com/weblog/images/md.jpg&w=200&h=191&ei=_lhXUK--C-nF0QGq5IHoBg&zoom=1&iact=rc&dur=407&sig=112060460161893400394&page=1&tbnh=142&tbnw=137&start=0&ndsp=23&ved=1t:429,r:2,s:0,i:158&tx=76&ty=101

topic definition statement

Stem Cell research is a topic that is talked about rarely. The basic knowledge is known except that there are different types and why research shows stem cells are important. They are publicized by the media rarely.  There are both pro’s and con’s on the issue.

This paper will examine stem cell research. What it is and the different types as well the pros and cons and the ethical issues surrounding the research.

“Stem Cell research ethically: Can it make a difference?”

Key question: “What impact can stem cell research have on cures for diseases? And is this ethical?”

Sub-questions: “ What cures have occurred since the use of stem cells and are there any negative views on the use of stem cells. How far has research come since the initial use of stem cells in the medical community? Is there any moral issues surrounding stem cell research in the harvesting and  use of stem cells?”

The sources I will use will be journals, web video , articles and book excerpts.

Annotated Bibliography

Lisa Filiczkowski

Annotated Bibliography

Stem Cell Information the National Institutes of research for stem cell research. Research Topics . In Stem Cell Information [World Wide Web site]. Bethesda, MD: National Institutes of Health, U.S. Department of Health and Human Services, 2010 [cited Sunday, September 09, 2012]  http://stemcells.nih.gov/info/basics/basics1.asp

Summary: The article answers many questions about stem cell research. It also goes on to define the reasons why it’s necessary to do stem cell research. The author is creditable because it is put out by the government for information to the public. The source lists many different links to different research.

Assess: The source will be useful when talking about stem cells there use and how they are need to cure many diseases and the ethical issues behind human embryonic stem cell research.

Reflect: I will be using this source when discussion the stem cell process and the ethical issues it has. This source has not changed my view on the topic.

The Regents of the university of Michigan. Stem cell research.  Ann Arbor Michigan 2012. http://www.stemcellresearch.umich.edu/donation/index.html

Summary: This article goes on to tell both donors and health care providers how to register and information for potential donors.

Assess: The source will be useful when directing my readers to information on how to become a donor for stem cell research. The authors are a creditable university currently conduction research on 3 different types of stem cells.

Reflect: I will be using this source when discussion to the reader the information on how to become a donor and info about the process. The source has not changed my view on the topic.

Popular Issues all about the Pros and Cons of stem cell Research. 2002-2012. There two footnotes mentioned.  http://www.allaboutpopularissues.org/pros-and-cons-of-stem-cell-research.htm

Summary: The Journal entry is a basic summary of what stem cells are and where they come from as well as the pros and cons of stem cell research.

Assess: The source will be extremely useful when it comes to the pros and con’s and the Understanding of where the stem cells come from and the different types of stem cells there are. The authors establishes creditability by footnoting the sources used to collect the info in the journal entry.

Reflect: I will be using this source when discussing different parts of stem cell research such as the pro’s and con’s and where they come from.

chapter 13 and 17

In this chapter it provides an overview of what the cells were used for and how the production of them assisted in creating many different vaccines. It also goes on to say that the cells were used in many areas of research because the cells were easily reproduced and were attained very cheap. It also goes on to tell the reader how a factory was created using the hela cells and marketing them all over the world. It also tells us briefly about the various areas it is used from cosmetics to pharmacological testing.
How can standardization limit the research growth?
Why are standardization procedures so important to scientific research?
Did the microbiological have the right to grow and sell Hela cell's?
In chapter 17 we learn of a virologist named Chester Southham we learn that this dr infected cancer patents with hela cells to create more tumors by lying to the patients.  He used prisoners and it was documented he placed cells in a surgical gyno patient. The nih placed guidelines for research and patients after he was charged and found guilty of wrong doing.
Why was this allowed to go on?
Eventually there were guidelines and laws put into place but why did the dr get away with this and what was he charged with for his wrong doing? Did him and his colleagues go to jail?

What topics you prefer to read

2/27/2012

The topic I prefer to read more on would be the treatment and the research that was done with the very first cells that were harvested.

• The chapter 13 on the Hela factory.
• The chapter 20 the HeLa bomb
• The research on the  “HeLa cell 50 years on:  The good, the bad and the ugly.” I think would be something that would interest me and answer my many questions. 

Chapters 1-5 of The Immortal life of Henrietta Lacks

Upon reading the initial prologue. The reader begins to get a basic background on who Henrietta Lacks is and that cells were cut from her cervix and given the name HeLa. We also learn that HeLa was derived from her first two initials in her first name and last name. It also goes on to tell us that her cells were used for various research in many different areas of medicine around the world. We also learn that many advances in medicine were also accomplished because of her cells. The reader also gets a vague understanding on why her cells are so important to medicine. Later in the reading we are introduced to a researcher named George Gey who was doing tissue culture research at the hospital she was at.  Mary the women who was a college graduate was hired because of her hands and what they could do when collecting all samples. The reader is informed because her cells didn't die they continued to grow and multiply why it was a huge break through in medical science. We also learn about her relationship she had with her children and husband. This was definitely a very loving mother and wife. She never passed judgement nor did she hold one's faults against anyone. She had a child that was placed in essentially a state hospital when she grew to big for her to care for any longer. Because of Henrietta's unconditional love for anyone in her life a piece of her was killed that day. According to the reading Henrietta was unaware that a sample of the tumor that was cut out of her and sent to see if they would survive. Henrietta shared with no one except her cousins that she felt like something was inside of her. The cousins assumed it was a child and in fact it was both. She would have her last child and then days later she would go on to discover by a self examination a hard substance in her cervix. This is what I found to be most interesting only because now days no women would think of doing what she did to discover the tumor in her cervix. The essential management of treatment to me seemed to be unbearable just by reading about her course of treatment and the procedures done to kill the tumors. The reader is introduced to Hopkins hospital. Which now day's is known all over the world. I believe it was because of her cells that made them a world renown Hospital. In the 5th chapter we learn that an important detail had not been told to Henrietta and that was because of her treatment she would never again  be able to have children. Something she was actually planning on doing after she was well enough. No one had informed her that because of the radium it would render patents infertile. The dr's acknowledge that a huge injustice was done to her. My groups questions were not answered actually in the chapters. When in fact they inform us that mistakes were made as far as informing the patent. I also learned that because she was a black women very little would be done for her. She suffered in pain and was not treated like a white person would have been if in her situation in that era of time.